. Author manuscript; available in PMC: 2016 Oct 1.

Published in final edited form as: Neurobiol Dis. 2015 Jun 6;82:164–175. doi: 10.1016/j.nbd.2015.05.016

Table 3.

mIPSC parameters from pyramidal neurons in layer II/III motor cortex

Age	Genotype	# cells	(-) peak amplitude (pA) ± SE	Frequency (Hz) ± SE	10-90% Rise time (ms) ± SE	Decay tau (ms) ± SE	(-) Charge transfer (pA X ms) (1^st – 3^rd quartile)
P35	WT	8	27.6 ± 2.5	4.9 ± 0.8	1.5 ± 0.2	7.0 ± 1.1	244 (190 - 453)

	KO	9	22.3 ± 2.2	6.8 ± 1.4	2.1 ± 0.3	15.0 ± 1.1	401 (249 - 666)

	AD	9	13.7 ± 0.9	4.6 ± 1.4	2.5 ± 0.3	12.5 ± 2.2	181 (94 - 338)

P120	WT	10	35.3 ± 4.9	4.2 ± 0.4	1.1 ± 0.1	8.6 ± 1.0	446 (436 - 546)

	KO	9	25.4 ± 3.5	6.9 ± 1.8	2.0 ± 0.3	9.9 ± 1.7	468 (403 - 532)

	AD	10	18.6 ± 2.0	1.6 ± 0.5	2.0 ± 0.2	13.7 ± 2.0	251 (172 - 334)

WT = wild type, KO = Het_α1KO, AD = Het_α1AD