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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Bone. 2015 Aug 20;81:413–416. doi: 10.1016/j.bone.2015.08.015

Table 1. Histomorphometry: Cortical bone.

WT PAPP-A KO
Vehicle PTH (%Δ) Vehicle PTH (%Δ)
BV/TV (%) 4.43 ± .060 4.76 ± 0.241 (+7) 4.36 ± 1.46 4.45 ± 0.265 (+2)
MS/BS (%) 17.2 ± 3.97 18.8 ± 4.79 (+9) 20.8 ± 1.50 20.0 ± 1.52 (-4)
BFR/BS (μm3/ μm2/d) 0.20 ± 0.035 0.27 ± 0.044 (+35) 0.25 ± 0.009 0.23 ± 0.016 (-8)
BFR/BV (%/d) 1.20 ± 0.201 1.90 ± 0.047* (+60) 1.90 ± 0.015 1.68 ± 0.212 (-12)
MAR (μm/d) 0.98 ± 0.015 1.50 ± 0.165* (+53) 1.22 ± 0.130 1.15 ± 0.078 (-6)

Results are presented as mean ± SEM of 3-4 mice per treatment group. Percent change with PTH compared to vehicle treatment is in parentheses.

*

Significant effect of PTH, P < 0.05

BV, bone volume

TV, total volume

BS, bone surface

MS, mineralizing surface

BFR, bone formation rate

MAR, mineral apposition rate