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. Author manuscript; available in PMC: 2016 Dec 1.

Published in final edited form as: Bone. 2015 Aug 20;81:413–416. doi: 10.1016/j.bone.2015.08.015

Table 1. Histomorphometry: Cortical bone.

	WT		PAPP-A KO
	Vehicle	PTH (%Δ)	Vehicle	PTH (%Δ)
BV/TV (%)	4.43 ± .060	4.76 ± 0.241 (+7)	4.36 ± 1.46	4.45 ± 0.265 (+2)
MS/BS (%)	17.2 ± 3.97	18.8 ± 4.79 (+9)	20.8 ± 1.50	20.0 ± 1.52 (-4)
BFR/BS (μm³/ μm²/d)	0.20 ± 0.035	0.27 ± 0.044 (+35)	0.25 ± 0.009	0.23 ± 0.016 (-8)
BFR/BV (%/d)	1.20 ± 0.201	1.90 ± 0.047^* (+60)	1.90 ± 0.015	1.68 ± 0.212 (-12)
MAR (μm/d)	0.98 ± 0.015	1.50 ± 0.165^* (+53)	1.22 ± 0.130	1.15 ± 0.078 (-6)

Results are presented as mean ± SEM of 3-4 mice per treatment group. Percent change with PTH compared to vehicle treatment is in parentheses.

^*

Significant effect of PTH, P < 0.05

BV, bone volume

TV, total volume

BS, bone surface

MS, mineralizing surface

BFR, bone formation rate

MAR, mineral apposition rate