Table 3. Clinical characteristics of NEC vs. no NEC group; 1:1matched.
| NEC (n=145) | No NEC (n=145) | P value | |
|---|---|---|---|
| Gestational age (week) | 26.6 ± 2.5 | 26.6 ± 2.6 | NS |
| Birth weight (g) | 837 ± 243 | 837 ± 243 | NS |
| Male, n (%) | 68 (46.9) | 79 (54.5) | NS |
| Antenatal steroid use | 105/137 (76.6) | 107/144 (74.3) | NS |
| PROM ≥ 18 hr | 47/142 (33.1) | 56 (38.6) | NS |
| Maternal chorioamnionitis | 40/111 (36.4) | 49/121 (40.5) | NS |
| Resuscitation at delivery | 139/143 (97.3) | 138/144 (95.8) | NS |
| Hypotension ≤ 1 week | 88(60.7) | 63 (43.4) | < 0.001 |
| RDS | 136 (93.8) | 133 (91.7) | NS |
| Pneumothorax | 22 (15.7) | 12 (8.3) | NS |
| Massive pulmonary hemorrhage | 22 (15.7) | 20 (13.8) | NS |
| Pulmonary hypertension | 19 (13.1) | 18 (1) | NS |
| IVH > grade II | 47 (32.4) | 28 (19.3) | 0.008 |
| Sepsis | 66 (45.5) | 48 (33.1) | 0.027 |
| PDA* | 87 (60.0) | 72 (49.7) | NS |
*PDA was defined when pharmacological or surgical treatment was intervened. g, gram body weight; PROM, premature rupture of membrane; RDS, respiratory distress syndrome; IVH, intraventricular hemorrhage; PVL, periventricular leukomalacia; PDA, patent ductus arteriosus.