Table 3.
Risk factors for distant metastases (M1) in multivariate logistic regression analysis: (A) considering TNM stage I, II, III, and IV at diagnosis; (B) considering only TNM stage I, II, and III at diagnosis
| OR (C.I. 95 %) | p | |
|---|---|---|
| (A) | ||
| Grading | 1.64 (1.25–2.15) | <0.05 |
| Histological type | ||
| Ductal invasive carcinoma | Referral | 1.000 |
| Lobular invasive carcinoma | 1.80 (1.21–2.65) | <0.05 |
| Ductal and lobular invasive carcinoma | 1.68 (1.07–2.64) | <0.05 |
| Other invasive carcinoma | 1.23 (0.60–2.51) | 0.570 |
| Molecular subtype | ||
| Luminal A | Referral | 1.000 |
| Luminal B | 1.86 (1.21–2.87) | <0.05 |
| Luminal Her | 2.34 (1.29–4.23) | <0.05 |
| Her enriched | 2.20 (1.15–4.22) | <0.05 |
| Basal-like | 2.89 (1.69–4.94) | <0.05 |
| Non described | 1.87 (1.20–2.93) | <0.05 |
| TNM | ||
| T1 | Referral | 1.000 |
| T2 | 1.53 (1.12–2.11) | <0.05 |
| T3 | 3.87 (2.16–6.92) | <0.05 |
| T4 | 2.62 (1.50–4.58) | <0.05 |
| N0 | Referral | 1.000 |
| N1 | 2.00 (1.41–2.85) | <0.05 |
| N2 | 4.26 (2.78–6.53) | <0.05 |
| N3 | 8.81 (5.81–13.37) | <0.05 |
| (B) | ||
| Grading | 1.55 (1.15–2.09) | <0.05 |
| Histological type | ||
| Ductal invasive carcinoma | Referral | 1.000 |
| Lobular invasive carcinoma | 1.96 (1.29–3) | <0.05 |
| Ductal and lobular invasive carcinoma | 1.5 (0.9–2.48) | 0.118 |
| Other invasive carcinoma | 0.79 (0.3–2.07) | 0.629 |
| Molecular subtype | ||
| Luminal A | Referral | 1.000 |
| Luminal B | 2.42 (1.48–3.97) | <0.05 |
| Luminal Her | 2.61 (1.33–5.13) | <0.05 |
| Her enriched | 2.28 (1.07–4.84) | <0.05 |
| Basal-like | 3.66 (2–6.72) | <0.05 |
| Non described | 2.26 (1.35–3.78) | <0.05 |
| TNM | ||
| T1 | Referral | 1.000 |
| T2 | 1.55 (1.09–2.19) | <0.05 |
| T3 | 3.12 (1.62–6.03) | <0.05 |
| T4 | 2.16 (1.13–4.13) | <0.05 |
| N0 | Referral | 1.000 |
| N1 | 2.23 (1.51–3.28) | <0.05 |
| N2 | 4.79 (3–7.63) | <0.05 |
| N3 | 7.95 (4.96–12.73) | <0.05 |