Fig. 5.
In vitro displacement of binding by non-labelled Cbl added after pre-incubation of a [57Co]Cbl and E. coli, b [57Co]Cbl and S. aureus and c of [99mTc]PAMA(4)-Cbl and S. aureus. Viable bacteria at 37 °C (empty bar), at 4 °C (filled bar) and non-viable bacteria after ethanol fixation (diagonal hatched, E. coli only). Significant differences between binding in the absence and in the presence of cold Cbl (at different concentrations) are indicated as follows: *P < 0.05, **P < 0.005, ***P < 0.0005. Note that X- and Y-axes are scaled depending on the bacterium or radiopharmaceutical tested.