Table 1.

Status of lab-grown kidney organoids.

Cell source	Description	References
IN VITRO
Embryonic cells	Suspension culture of dissociated-reaggregated chick mesonephric cells	Moscona and Moscona, 1952
	Culture at air–medium interface of dissociated- reaggregated mouse metanephric cells	Unbekandt and Davies, 2010
Adult cells	Collagen matrix embedded murine and human renal cells	Joraku et al., 2009; Guimaraes-Souza et al., 2012
PSC- derived cells	2-dimensional culture of 18 day differentiated hPSC	Takasato et al., 2014
	14-day differentiated EBs induced with mouse embryonic spinal cord	Taguchi et al., 2014
IN VIVO
Embyonic cells	Mouse metanephric cells cultured on CAM of avian embryos	Preminger et al., 1980
	Rat metanephroic cells transplanted in the omentum of a rat	Hammerman, 2002
	Mouse metanephric cells cultivated in mouse lymph node	Francipane and Lagasse, 2015
PSC-derived cells	Mouse embryonic spinal cord-induced EBs transplanted under the kidney capsule of mice	Taguchi et al., 2014
	Sall1- deficient mouse blastocyst, complemented with wildtype mouse PSCs	Usui et al., 2012