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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Bone. 2015 Jul 15;81:145–151. doi: 10.1016/j.bone.2015.07.013

Table 3.

Lean mass index and fat mass index individually regressed on HRpQCT outcomes by sex with adjustment for covariates*.

Lean mass index Fat mass index
Men Women Men Women
Beta (95% CI) p-value Beta (95% CI) p-value Beta (95% CI) p-value Beta (95% CI) p-value
Total area (mm2) R 4.02 (−5.11,13.15) 0.386 4.63 (−0.05,9.32) 0.053 −4.47 (−9.32,0.38) 0.071† 1.41 (−0.61,3.42) 0.171†
T 6.38 (−10.08,22.83) 0.445 4.41 (−6.15,14.96) 0.411 −5.26 (−14.01,3.49) 0.237 2.19 (−2.38,6.76) 0.344
Cortical area (mm2) R 2.90 (1.35,4.44) <0.001 † 1.38 (0.48,2.28) 0.003 † 0.72 (−0.13,1.57) 0.098 0.48 (0.09,0.86) 0.017
T 7.91 (5.10,10.72) <0.001 † 4.49 (2.93,6.05) <0.001 † 2.70 (1.12,4.29) 0.001 1.56 (0.85,2.26) <0.001
Cortical thickness (μm) R 33.47 (11.70,55.24) 0.003 9.28 (−8.75,27.32) 0.311 12.48 (0.67,24.29) 0.038 3.40 (−4.33,11.13) 0.386
T 60.34 (32.78,87.90) <0.001 † 33.16 (13.74,52.58) 0.001 † 22.40 (7.24,37.57) 0.004 9.50 (0.90,18.10) 0.031
Cortical density (mg/cm3) R 2.58 (−2.91,8.06) 0.355 −3.21 (−9.63,3.22) 0.325 −0.73 (−3.71,2.25) 0.630 −0.52 (−3.28,2.23) 0.707
T 4.41 (−2.27,11.09) 0.194 6.52 (−0.32,13.36) 0.061 0.63 (−2.96,4.22) 0.731 3.43 (0.49,6.38) 0.023
Cortical porosity (%) R 0.06 (−0.09,0.22) 0.419 0.06 (−0.09,0.22) 0.414 0.07 (−0.01,0.15) 0.097 0.00 (−0.06,0.07) 0.956
T 0.08 (−0.19,0.36) 0.559 0.03 (−0.26,0.32) 0.832 0.11 (−0.04,0.25) 0.158 0.02 (−0.11,0.14) 0.788
Trabecular area (mm2) R 1.78 (−6.93,10.50) 0.686 3.50 (−1.35,8.35) 0.156 −4.17 (−8.79,0.45) 0.076† 1.11 (−0.97,3.19) 0.294†
T −2.38 (−19.24,14.49) 0.781 0.39 (−10.80,11.57) 0.946 −8.72 (−17.63,0.18) 0.055† 0.88 (−3.97,5.72) 0.721†
Trabecular density (mg/cm3) R 1.98 (−2.21,6.17) 0.352 3.16 (−1.34,7.67) 0.167 1.79 (−0.44,4.02) 0.115 2.18 (0.27,4.09) 0.025
T 1.97 (−1.93,5.88) 0.320 1.44 (−2.80,5.69) 0.503 2.50 (0.45,4.55) 0.017 1.50 (−0.32,3.33) 0.105
Trabecular number (cm−1) R 0.23 (−0.05,0.51) 0.108 0.40 (−0.03,0.83) 0.070 0.19 (0.04,0.33) 0.014 0.29 (0.11,0.47) 0.002
T 0.54 (0.23,0.86) 0.001 0.59 (0.22,0.96) 0.002 0.44 (0.28,0.60) <0.001 0.34 (0.18,0.49) <0.001
Trabecular thickness (μm) R 0.06 (−1.10,1.21) 0.925 0.01 (−1.13,1.14) 0.992 0.13 (−0.49,0.75) 0.684 −0.00 (−0.49,0.48) 0.993
T −0.78 (−1.87,0.30) 0.154 −0.96 (−2.24,0.32) 0.141 −0.27 (−0.85,0.31) 0.362 −0.38 (−0.94,0.17) 0.177
Trabecular separation (μm) R −5.59 (−12.74,1.56) 0.124 −9.08 (−24.50,6.34) 0.246 −3.45 (−7.27,0.37) 0.076 −7.43 (−13.95,−0.92) 0.026
T −7.75 (−13.62,−1.89) 0.010 −12.05 (−21.25,−2.85) 0.011 −6.79 (−9.81,−3.77) <0.001 −6.43 (−10.37,−2.49) 0.002

Key: In bold if p<0.05. R, radius; T, tibia.

*

Covariates are age at HRpQCT scan, smoking status, alcohol consumption, calcium intake, vitamin D intake, physical activity and social class; with additional adjustment for years since menopause and HRT use in women.

†

Significant sex interaction (p<0.05).