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. 2015 Nov 11;13:94. doi: 10.1186/s12915-015-0208-3

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© Verna et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Summary and interpretations. a. Unique and redundant functions of PIN1, PIN5, PIN6, and PIN8 in vein network formation (magenta, inhibiting functions; green, promoting functions), and derived mutant phenotypes. It is possible that PIN8’s functions extend to overlap with PIN6’s in PIN1-dependent inhibition of vein network formation. b. Genetic interaction map of PIN1, PIN5, PIN6, and PIN8 in vein network topology. Arrows indicate positive effects; blunt-ended lines indicate negative effects. c. DR5-promoter-activity-derived auxin levels and distribution in developing leaves (left; lower levels are in lighter tints; for simplicity, differences within leaves are ignored), and vein networks in mature leaves (right). d. Cellular expression map of PIN1, PIN5, PIN6, and PIN8 in vein development. See text for details