Table 1.
Association between SOX4 expression and clinicopathological parameters in patients with oral squamous cell carcinoma
Parameters | SOX4 expression | p-value | ||
---|---|---|---|---|
Total (n = 85) | Low (n = 41) | High (n = 44) | ||
Age (yr) | 0.161 | |||
<64 | 41 | 23 | 18 | |
≥64 | 44 | 18 | 26 | |
Sex | 0.492 | |||
Male | 61 | 28 | 33 | |
Female | 24 | 13 | 11 | |
Location | 0.654 | |||
Oral tongue | 60 | 28 | 32 | |
FOM, BM, RMT | 25 | 13 | 12 | |
Stage | 0.651 | |||
I, II | 56 | 28 | 28 | |
III, IV | 29 | 13 | 16 | |
T stage | 0.843 | |||
T1, T2 | 74 | 36 | 38 | |
T3, T4 | 11 | 5 | 6 | |
N stage | 0.327 | |||
N0 | 60 | 31 | 29 | |
N1, N2 | 25 | 10 | 15 | |
CRT | 0.622 | |||
No | 35 | 23 | 27 | |
Yes | 50 | 18 | 17 | |
Recurrence | 0.004 | |||
No | 53 | 32 | 21 | |
Yes | 32 | 9 | 23 | |
Treatment failure | 0.032 | |||
No | 59 | 33 | 26 | |
Yes | 26 | 8 | 18 |
FOM = floor of mouth; BM = buccal mucosa; RMT = retromolar trigone; CRT = chemotherapy and/or radiotherapy; χ2 test and Fisher’s exact test was used