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. Author manuscript; available in PMC: 2016 Apr 8.
Published in final edited form as: Nature. 2015 Sep 28;526(7572):273–276. doi: 10.1038/nature14904

Figure 1. CDK8 is asymmetrically loaded at SEs in MOLM-14 cells.

Figure 1

(a) Clustering of total ChIP-seq signal of CDK8, MED1, BRD4, H3K27ac, RNA pol II, and H3K4me1 on CDK8 positive regions. Each respective cluster is ordered by CDK8 signal. The red bar indicates the cluster most highly enriched for the factors listed above. (b) Overlap between SEs independently identified by ChIP-seq signal for CDK8, MED1 and BRD4 based on the collapsed superset of regions identified by any one factor. (c) ChIP-seq binding profiles at the CEBPA locus.