Table 2.
Baseline and week 8 31P-MRS results for female adolescents with MDD vs. healthy controls.
Phosphorus metabolite | Major depressive disorder (n=5)
|
Healthy controls (n=6)
|
||||
---|---|---|---|---|---|---|
Mean baseline (SD) | Mean 8 weeks (SD) | p-value | Mean baseline (SD) | Mean 8 weeks (SD) | p-value | |
PCr/TP | 0.1513 (0.0137) | 0.1610 (0.0165) | 0.020 | 0.1556 (0.0086) | 0.1558 (0.0154) | 0.969 |
β-NTP/TP | 0.1254 (0.0087) | 0.1280 (0.0125) | 0.729 | 0.1203 (0.0048) | 0.1253 (0.0109) | 0.329 |
pH | 7.059 (0.1383) | 7.0712 (0.0359) | 0.648 | 7.0526 (0.0290) | 7.0294 (0.0143) | 0.054 |
PCr/β-NTP | 1.221 (0.0528) | 1.2700 (0.1380) | 0.528 | 1.2962 (0.1005) | 1.2584 (0.2172) | 0.645 |
Paired t-test, 2-tailed.
PCr: Phosphocreatine.
β-NTP: beta-Nucleoside Triphosphate.
TP: Total Phosphorus Resonance.
P MRS: 31-Phosphorus Magnetic Resonance Spectroscopy.
SD: Standard Deviation.