Table 2. Concentrations of cytochrome P450 in the mouse livers of the flight group (SF), ground control (GC), and recovery group (RA).
CYP | SF, fmol\μg of total protein a | GC, fmol\μg of total protein a | RA, fmol\μg of total protein a |
---|---|---|---|
1A1 | 0.53 ± 0.04 | 0.46 ± 0.12 | 0.78 ± 0.10**, *** |
1A2 | 11.18 ±0.65* | 5.94 ± 1.79 | 2.45 ± 1.59*** |
2D9 | 9.90 ± 2.40 | 7.10 ± 3.23 | 2.34 ±1.54**,*** |
2D10 | 11.40 ± 2.10 | 13.28 ± 1.28 | 11.31 ± 3.98 |
2D26 | 11.06 ± 1.82 | 13 ± 3.28 | 14.94 ± 8.70 |
2E1 | 33.45 ± 3.62* | 18.51 ± 3,43 | 35.72 ± 3.13** |
3A11,16 | 7.85 ± 4.37 | 7.97 ± 1.07 | 6.03 ± 0.91 |
3A11,41 | 4.46 ± 2.68 | 5.96 ± 0.32 | 7.62 ± 4.08 |
2C29 | 67.89 ± 5.10* | 46.92± 7.09 | 40.83 ± 9.33*** |
2C39 | 2.26 ± 1.77 | 1.66 ± 0.54 | 4.44 ± 0.56 |
2C50,54 | 21.15 ± 5.7 | 14.41 ± 3.89 | 16.41± 2.91 |
a means±SE of 4 separate experiments for SF and GC conditions and 3 separate experiments for RA condition
* statistically significant difference between SF and GC groups (p-value < 0.05)
** statistically significant difference between RA and GC groups (p-value < 0.1)
*** statistically significant difference between SF and RA groups (p-value < 0.1)