Table 1. Domains of databases with potential for use in HTA^*.

Domain	Outcomes/variables
Safety/Efficacy/ Effectiveness	Mortality
	Morbidity
	Disability
	Adverse event
	Quality of life (e.g. EQ-5D, SF36, HUI)
	Life year, Quality-adjusted life year
Social/ethical	Compliance
	Acceptance
	Satisfaction
Organizational/professional	Utilization (e.g. service or technology utilization)
	Length of stay
	Personnel required
	Material required (e.g. hospital bed)
Economic	Cost/price
	Income/economic status
Epidemiological	Prevalence
	Incidence
	Health state
	Demographic (e.g. age, sex, education)

Adapted from Draborg et al [1] and Velasco et al.2002 [16]

* HTA, Health technology assessment; EQ-5D, European Quality of Life-5 Dimensions; SF36, Medical Outcomes Study 36-Item Short-Form Health Survey; HUI, Health Utility Index