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. 2015 Nov 11;10(11):e0142480. doi: 10.1371/journal.pone.0142480

Table 2. Cumulative incidence (per 100,000) of kidney cancer from 2003 to 2005 in diabetic patients and non-diabetic people by age and the unadjusted odds ratios comparing diabetic patients to non-diabetic people.

Age Type 2 diabetes mellitus Odds ratio (95% confidence interval) P
Yes No
n / N 3-year cumulative incidence n / N 3-year cumulative incidence
Diabetes mellitus of any duration
All ages 193 / 115655 166.9 292 / 883073 33.1 5.1 (4.2–6.1) <0.01
Age <40 years 8 / 17270 46.3 42 / 570472 7.4 6.3 (3.0–13.4) <0.01
Age 40–64 years 57 / 57199 99.7 147 / 253826 57.9 1.7 (1.3–2.3) <0.01
Age 65–74 60 / 23181 258.8 60 / 34486 174.0 1.5 (1.0–2.1) <0.05
Age ≥75 68 / 18005 377.7 43 / 24289 177.0 2.1 (1.5–3.1) <0.01
Sensitivity analysis after excluding patients with diabetes mellitus diagnosis for <5 years
All ages 129 / 69494 185.6 292 / 883073 33.1 5.6 (4.6–6.9) <0.01
Age <40 years 2 / 8586 23.3 42 / 570472 7.4 3.2 (0.8–13.1) 0.11
Age 40–64 years 34 / 32361 105.1 147 / 253826 57.9 1.8 (1.3–2.6) <0.01
Age 65–74 41 / 15716 260.9 60 / 34486 174.0 1.5 (1.0–2.2) <0.05
Age ≥75 52 / 12831 405.3 43 / 24289 177.0 2.3 (1.5–3.4) <0.01

n: case number of kidney cancer, N: case number observed