Table 3. DTI results: Group comparison and correlation analysis with ToM in PD.
Brain Area | Cluster size (voxels) | MNI coordinate | t value | p value | Effect size (Cohen´s d / r) df = 36 | ||
---|---|---|---|---|---|---|---|
x | y | z | |||||
Group Comparison | |||||||
FA | |||||||
R Uncinate Fasciculus | 42 | 34 | 15 | -13 | 2.95 | .001* | .81 |
Correlation with ToM in PD | |||||||
FA | |||||||
R Superior Longitudinal Fasciculus | 97 | 23 | -29 | 42 | 5.18 | .032** | .65 |
MD | |||||||
L Superior longitudinal Fasciculus | 13046 | -40 | -55 | 36 | 5.86 | .031** | .69 |
259 | -31 | 14 | 28 | 5.20 | .040** | .65 | |
L External Capsule | 483 | -33 | 3 | 4 | 4.14 | .039** | .56 |
RD | |||||||
L Superior Longitudinal Fasciculus | 650 | -30 | -10 | 14 | 3.8 | .040** | .53 |
Correlation with ToM in PD controlling for Executive Functions | |||||||
FA | |||||||
R Superior Longitudinal Fasciculus | 227 | 28 | -26 | 43 | 2.61 | .002* | .39 |
MD | |||||||
L Superior Longitudinal Fasciculus | 1322 | -40 | -55 | 35 | 5.33 | .049** | .66 |
878 | -19 | -45 | 43 | 3.93 | .043** | .54 | |
L Inferior Longitudinal Fasciculus | 165 | -31 | -69 | -1 | 4.04 | .049** | .55 |
RD | |||||||
R Corticoespinal Tract | 296 | 14 | -13 | 66 | 1.24 | .002* | .20 |
124 | -27 | -20 | 63 | 0.86 | .001* | .14 | |
L Inferior Longitudinal Fasciculus | 169 | -27 | -63 | 47 | 1.69 | .001* | .27 |
115 | -28 | -8 | -16 | 1.23 | .001* | .20 | |
L Superior Longitudinal Fasciculus | 109 | -58 | -26 | 6 | 1.31 | .002* | .21 |
Cluster size denotes the extent of the cluster of significant voxels. MNI coordinates refer to the location of the most statistically significant voxel in the cluster.
*Differences are significant at p < .001 uncorrected.
**Differences are significant at p < .05 corrected for family-wise error (FWE).
PD = Parkinson’s disease; ToM = Theory of Mind; R = Right; L = Left; FA = Fractional Anisotropy; MD = Mean Diffusivity; RD = Radial Diffusivity; MNI = Montreal Neurological Institute; df = Degrees of Freedom.