Table 2. Drug susceptibility testing results for multidrug resistant tuberculosis patients in Estonia, Latvia and Romania in 2013.
Estonia | Latvia | Romania | ||||
---|---|---|---|---|---|---|
New cases | Retreatment cases | New cases | Retreatment cases | New cases | Retreatment cases | |
# (%) | # (%) | # (%) | # (%) | # (%) | # (%) | |
Total | 29 | 21 | 50 | 26 | 165 | 410 |
Number undergoing 1st line DST | 29 (100.0) | 21 (100.0) | 50 (100.0) | 26 (100.0) | 165 (100.0) | 410 (100.0) |
Additional resistance to… | ||||||
Ethambutol | 27 (96.4) a | 20 (95.2) | 36 (72.0) | 21 (80.8) | 68 (70.1) b | 195 (76.5) b |
Pyrazinamide | 20 (71.4) a | 15 (71.4) | 36 (75.0) c | 18 (69.2) | Not tested | Not tested |
Number undergoing 2nd line DST | 28 (96.6) | 21 (100.0) | 50 (100.0) | 26 (100.0) | 108 (65.5) | 276 (67.3) |
Additional resistance to… | ||||||
Amikacin | 3 (10.7) | 3 (14.3) | 22 (44.0) | 9 (34.6) | 9 (13.6) b | 51 (33.1) b |
Capreomycin | 3 (10.7) | 3 (14.3) | 25 (50.0) | 15 (57.7) | 13 (18.6) b | 61 (37.2) b |
Kanamycin | 5 (17.9) | 9 (42.9) | 21 (42.9) d | 15 (57.7) | 18 (20.7) b | 94 (40.2) b |
Ofloxacin | 10 (35.7) | 9 (42.9) | 9 (18.0) | 8 (30.8) | 13 (18.8) b | 48 (31.6) b |
Moxifloxacin | 2 (10.5) e | 2 (16.7) e | Not tested | Not tested | Not tested | Not tested |
Cycloserine | Not tested | Not tested | 1 (2.0) | 0 (0.0) | 2 (7.1) b | 17 (16.2) b |
PAS | Not tested | Not tested | 12 (25.0) c | 5 (19.2) | 5 (8.3) b | 14 (9.3) b |
Prothionamide | 4 (14.3) | 9 (42.9) | 26 (52.0) f | 19 (73.1) f | 10 (11.2) f | 27 (12.3) f |
Linezolid | 0 (0.0) g | 2 (14.3) g | Not tested | Not tested | Not tested | Not tested |
aDenominator 28
bdenominators (new cases, retreatment cases) ethambutol 97, 255; amikacin 66, 154; capreomycin 70, 164; kanamycin 87, 234; ofloxacin 69, 152; cycloserine 28, 105; PAS 60, 151
cdenominator 48
ddenominator 49
edenominator 19 new, 12 retreatment
fethionamide DST undertaken in Latvia and Romania (denominators for new Romanian cases 89, retreatment cases 220)
gdenominator 21 new, 14 retreatment. DST- drug susceptibility testing; PAS- p-aminosalicylic acid.