Table 2. A list of IDH mutant glioma patients with (A) and without (B) +7q, +8q, −9p, and/or −11p according to comparative genomic hybridization (CGH) analysis as well as their prognosis and TP53 mutation status.
| A | |||||||||
| Histology | Age, Sex | Surgery | CNAs | Genetic type | TP53 mut | Tumor regrowth | PFS, mo | Follow-up, mo | Outcome |
| A GII | 22M | 1 st | +8q21.3-ter, +10pter-q23, −10q25-ter, −X | +8q | NA | No | 85 | 85 | Alive |
| A GII* 1 | 25M | 1 st | −4q22-ter, +5pter-23.3, −5q31.2-ter, +7, +8q, +13, −19q, −22 | +8q | NA | Yes | 15 | 25 | Dead |
| A GII | 27M | 1 st | +7q31.3-ter, +10, +20 | +7q | p.K132fs | No | 30 | 30 | Alive |
| A GII | 28F | 1 st | −6q, +8q21.1-ter, −9p, −14q22-ter, −Xp | +8q, −9p | NA | Yes | 62 | 77 | Dead |
| A GII | 30F | 1 st | −6q, −9p, −14q22-ter, −19q | −9p | p.D281G | Yes | 41 | 67 | Alive |
| A GII* 2 | 33M | 1 st | +8q22.3-ter, −12q13-24.1 | +8q | p.R273H | Yes | 12 | 83 | Alive |
| A GII | 35F | 1 st | −4q, +6petr-q21, −8p21, +8q21.1–22, −13q22-ter, −14q21-ter | +8q | NA | Yes | 76 | 76 | Alive |
| A GII* 3 | 44F | 1 st | −3p22-21, +7q, +8q22-ter, +11q23.3-ter, +12p, −13q21-31, −19q | +7q, +8q | p.R273C | Yes | 27 | 65 | Dead |
| A GII | 45M | 1 st | +8q21.1–24.1, −11q23-ter, +19 | +8q | NA | No | 48 | 48 | Alive |
| A GII | 46F | 1 st | +7q, −19q | +7q | p.H179Y | No | 14 | 14 | Alive |
| A GII | 54F | 1 st | −4q, +8, +10pter-q22.3, −11p | −11p | p.N247S | No | 15 | 15 | Alive |
| A GII | 56F | 1 st | +7q, −10, +19q, +20 | +7q | NA | Yes | 5 | 9 | Dead |
| A GII | 57F | 1 st | +1q31-ter, −11p, +12p, −12q12-22, +12q23-ter, −18, −19q, −20p, −21 | −11p | NA | No | 2 | 2 | Alive |
| A GIII | 27F | 1 st | −3p21-13, +7p, +8q, +10p, −13q, +14q24.3-ter, −16q, −19q, −X | +8q | NA | Yes | 13 | 32 | Dead |
| A GIII | 35F | 1 st | −11, −17p, −18q, −20p | −11p | p.R175H | Yes | 31 | 37 | Dead |
| A GIII | 35M | 1 st | −11, −12q | −11p | p.R273C | No | 9 | 9 | Alive |
| A GIII | 39F | 1 st | +1q21-31, −1q32.2-ter, +2p16-11.2, −5q, −6q, +7q, +8q23-ter, −9q22-33, −10p, +17q, −19q, −Xp | +7q, +8q | NA | No | 18 | 18 | Alive |
| A GIII | 40F | 1 st | +10q23-ter, −11, −13, −14, −17p, +17q, −18 | −11p | NA | Yes | 4 | 4 | Alive |
| A GIII | 43M | 1 st | +8q, +12p, -19q, +20, +X | +8q | NA | Yes | 50 | 50 | Alive |
| A GIII | 47F | 1 st | −8p, −9p, +9q, −10q24-ter, +12q14-15, −12q21-ter, −14q21-31 | −9p | p.R273C | Yes | 21 | 36 | Dead |
| A GIII* 4 | 48M | 1 st | −4q13-21, +7q, +13q31-ter, +X | +7q | p.R175H | Yes | 51 | 67 | Dead |
| A GIII* 4 | 52M | 2 nd | +2pter-22, +3pter-23, +4q21-24, +4q26-33, −6pter-22, −6q21-ter, +7q,−9pter-21, −12p13, +20q | +7q, −9p | p.R175H | Yes | 1 | 67 | Dead |
| A GIII | 55M | 1 st | −2pter-23, +2p21-13, +3pter-22, +3q24.1-ter, −4q28, +8p, −8q12-13, +8q21.3–22.3, −9p, −10q22.1-ter, +12q13.1–23, −13q12.1–22, −17p, +17q, +19q, −20p | +8q, −9p | NA | Yes | 3 | 26 | Dead |
| A GIII | 59F | 1 st | −4q, −5p, +7, +8q | +8q | NA | No | 10 | 10 | Alive |
| A GIII | 65F | 1 st | +1p35-33, +1q, +3p22-21, -6, +7p, +7q32-ter, +8q23-ter, +9pter-21, -9q, −10q, −13, −14, +15q, -22q | +7q, +8q | p.R244S, p.R245D | Yes | 10 | 30 | Dead |
| A GIII* 5 | 74F | 2 nd | +1p21, +1q, +7p15-cen, +8q21.3, +10p, +16p11.2, +16q | +8q | p.A138V | No | 13 | 19 | Dead |
| OA GII* 6 | 34M | 1 st | −1p, +2p, −9p, −19q | −1p/19q, −9p | none | Yes | 25 | 34 | Alive |
| OA GII* 7 | 39M | 1 st | +7q, +10q24-ter | +7q | p.R175H | Yes | 47 | 60 | Alive |
| OA GII* 7 | 43M | 2 nd | −5p, +7q, −18q | +7q | p.R175H | No | 11 | 60 | Alive |
| OA GII | 46F | 1 st | +3p, −5p, +8, −11p, −13q12.1–21.3, +13q22-ter | −11p | p.R306X | No | 19 | 19 | Alive |
| OA GI * 8 | 61F | 1 st | +7q31-ter, −X | +7q | p.Y163C | Yes | 20 | 74 | Alive |
| OA GII* 8 | 63F | 2 nd | +7q31.1-ter, +12q22-ter, −Xp | +7q | p.Y163C | No | 7 | 74 | Alive |
| OA GIII* 9 | 30M | 2 nd | −1p, −4, +7q21.3-ter, +8, +11, −14q22-23, −18, −19q | −1p/19q, +7q | none | Yes | 16 | 111 | Alive |
| OA GIII* 2 | 34M | 2 nd | +4p, −4q, −5qcen-13, −5q21-ter, +8q13-ter, −9pter-21.3, −11p, +12p, −12q22-23 | +8q, −9p, −11p | p.R273H | Yes | 48 | 83 | Alive |
| OA GIII | 36F | 1 st | −1q41-ter, −6q, +7q31-ter, −9p, −14q22-ter, −Xq21-ter | +7q, −9p | p.G245S | No | 36 | 36 | Alive |
| OA GIII | 40F | 1 st | −1p, +1q, +3, −9, +12q14, −15q, +17, +18, −19q, +20 | −1p/19q, −9p | none | Yes | 105 | 115 | Alive |
| OA GIII* 10 | 44F | 3 rd | +2p, −3p21.3–11.2, +7, +8q23-ter, +10pter-12.3, −19q13.2-ter | +8q | p.Y220C | Yes | 2 | 80 | Alive |
| OA GIII* 3 | 47F | 2 nd | −4q28-ter, +7q, +8q23-ter, +12p, −Xq | +7q, +8q | p.R273C | Yes | 29 | 65 | Dead |
| OA GIII* 5 | 74F | 1 st | +1p21, +1q, +2p16-ter, +2q, −3p21, +7p21, +7qcen-21, +8, +10p, +10qcen-24, +11, +12p, -12q14-23, +16q | +7q | p.A138V | Yes | 6 | 19 | Dead |
| O GII | 57F | 1 st | −1p, −9pter-21, −18, −19q, +21 | −1p/19q, −9p | none | No | 51 | 51 | Alive |
| O GII | 59M | 1 st | +7q, +8q21.1-ter, +10p, −13q14-32, −16q, −19q | +7q, +8q | p.R248W | No | 36 | 36 | Alive |
| O GII | 71M | 1 st | −6pter-16, +8q21.1–21.3 | +8q | NA | No | 40 | 40 | Alive |
| O GIII* 11 | 37F | 2 nd | −1p, +1q, −2, +6, +7, +8, −9, +11, −16, +17, −18, +19p, −19q, +21, −22 | −1p/19q, −9p | none | No | 8 | 26 | Alive |
| O GIII | 41M | 5 th | −1p, +7q, +8, +18p, −18q, −19q, +22q | −1p/19q, +7q | none | Yes | 5 | 76 | Dead |
| O GIII | 62M | 1 st | −1p, +7q31.1-ter, −19q | −1p/19q, +7q | none | No | 0 | 0 | Dead |
| O GIII* 12 | 64M | 2 nd | −1p, +2, +7, −9p, +9q, −15q, −19q | −1p/19q, −9p | none | Yes | 27 | 134 | Alive |
| O GIII | 72M | 1 st | +1q, −2q37, −4p, +4q, −6pter-21.3, −6q16-ter, −8, −9pter-23, −11p, −14q, −17p, +17q22-ter | −9p, −11p | p.R248W | Yes | 4 | 15 | Dead |
| GBM* 1 | 26M | 2 nd | −3q11.2–24, +3q24.1-ter, +4p, −4q, +5pter-5q23.3, −5q31.2-ter, −6pter-22.1, +6p22.2–18.3, −6q21-26, +7, +8q, −9p, +13, −14q, +16q, +17q, −18, −19q, +21, −22 | +8q, −9p | none | Yes | 1 | 25 | Dead |
| GBM* 13 | 28F | 2 nd | −3pter-3q24, −5p, +7, −11p, −11q22-23.1, −13q, −19q, −22, −X | −11p | p.Y220C, p.R248W | No | 24 | 102 | Alive |
| GBM* 14 | 28M | 3 rd | −4q28-ter, +5pter-q23.3, +7q, +8q, −9p, −9q, −11pter-15.1, −11q23.1-ter, +12p, −13q21.1–22, +13q31-ter | +7q, +8q, −9p | p.Y236D | Yes | 4 | 67 | Dead |
| GBM | 62M | 1 st | +2, −6p, −7p, +7q, +8q22-ter, −9p, +9q, −11, −13q, −14q, +15q, +18q21 | +7q, +8q, −9p, −11p | NA | Yes | 3 | 4 | Dead |
| ND* 14 | 26M | 1 st | +7q, +8q22.1-ter, +11q23.3-ter, +12p, +19 | +7q, +8q | NA | Yes | 27 | 67 | Dead |
| ND* 14 | 30M | 4 th | +7q, +8q, −9p, −X | +7q, +8q, −9p | p.Y236D | Yes | 4 | 67 | Dead |
| ND* 2 | 38M | 3 rd | −5q31.1-ter, +8q22.3-ter, +10p, −10q, +12p | +8q | p.R273H | No | 20 | 83 | Alive |
| B | |||||||||
| A GII* 13 | 22F | 1 st | −11q22-23.1 | another | p.Y220C, p.R248W | Yes | 78 | 102 | Alive |
| A GII* 15 | 22F | 1 st | none | none | p.H193Y | Yes | 72 | 85 | Alive |
| A GII | 37M | 1 st | +2q24-33, −3p22-q25, −4q28-ter, +7 | another | NA | No | 7 | 7 | Alive |
| A GII | 38F | 1 st | −1p, −19q | −1p/19q | none | No | 14 | 14 | Alive |
| A GII | 41M | 1 st | −4 | another | p.H179R | No | 9 | 9 | Alive |
| A GIII | 55M | 1 st | −1p, +7, −10p, −19q | −1p/19q | NA | No | 12 | 12 | Alive |
| A GIII | 60M | 1 st | −1p, −4, −9q22-ter, −14q21.3-ter, −19q | −1p/19q | NA | No | 118 | 118 | Alive |
| OA GII* 9 | 24M | 1 st | −1p, −19q | −1p/19q | none | Yes | 69 | 111 | Alive |
| OA GII | 31F | 1 st | −12q, −13q14.3–22 | another | none | No | 5 | 5 | Alive |
| OA GII | 34F | 1 st | −1p, −19q | −1p/19q | none | No | 55 | 55 | Alive |
| OA GII | 34M | 1 st | −1p, −14q, −19q | −1p/19q | none | No | 161 | 161 | Alive |
| OA GII* 16 | 35F | 1 st | −1p, −19q | −1p/19q | none | Yes | 52 | 102 | Alive |
| OA GII | 37M | 1 st | −1p, −14, −19q | −1p/19q | none | Yes | 35 | 35 | Alive |
| OA GII* 10 | 40F | 2 nd | +7 | another | p.Y220C | Yes | 22 | 80 | Alive |
| OA GII | 41M | 1 st | −4q26-ter, −5q21-ter, +7, −11q, −12q | another | none | No | 79 | 79 | Alive |
| OA GII | 41F | 1 st | −1p, −19q | −1p/19q | none | No | 43 | 43 | Alive |
| OA GII | 44F | 1 st | −1p, −14q, −19q | −1p/19q | none | No | 81 | 81 | Alive |
| OA GII | 45F | 1 st | −1p, +7, −19q | −1p/19q | none | No | 5 | 5 | Alive |
| OA GII | 48M | 1 st | −1p, −19q | −1p/19q | none | No | 39 | 39 | Alive |
| OA GIII* 15 | 28F | 2 nd | −13q22, +18p, +19, −X | another | p.H193Y | No | 4 | 85 | Alive |
| OA GIII* 17 | 29M | 1 st | −1p, −19q | −1p/19q | none | Yes | 49 | 68 | Alive |
| OA GIII* 9 | 32M | 3 rd | −1p, +3, −4, +5, +7, +9q, +10p, −10q, −13q, −15q11.2–22.3, +15q22.2-ter, −19q | −1p/19q | none | Yes | 11 | 111 | Alive |
| OA GIII* 17 | 34M | 2 nd | −1p, −19q | −1p/19q | none | No | 9 | 68 | Alive |
| OA GIII | 35M | 1 st | −1p, −4, −13, −18, −19q | −1p/19q | none | No | 40 | 40 | Alive |
| OA GIII | 36M | 1 st | −1p, −4, +11, −19q | −1p/19q | none | No | 116 | 116 | Alive |
| OA GIII | 37F | 1 st | −1p, −14q13-24, −19q | −1p/19q | none | No | 151 | 151 | Alive |
| OA GIII | 43M | 1 st | −1p, +1q12-32.1, −1q32.2-ter, +11, +17, +19p, −19q | −1p/19q | none | Yes | 44 | 64 | Dead |
| OA GIII | 44M | 1 st | −1p, −19q | −1p/19q | none | No | 11 | 11 | Alive |
| OA GIII | 74M | 1 st | +1q, +3, +4q12-24, −5q13.1–14, +9p, −14q, −18p | another | NA | No | 3 | 3 | Alive |
| O GII | 33M | 1 st | −1p, −14q22-24.3, −19q | −1p/19q | NA | No | 15 | 15 | Alive |
| O GII* 18 | 34M | 1 st | −1p, −14, −19q | −1p/19q | none | Yes | 63 | 69 | Alive |
| O GII | 52F | 1 st | −1p, −4, +7, +11q, −15q21-ter, −18q, −19q | −1p/19q | NA | No | 12 | 12 | Alive |
| O GII* 12 | 53M | 1 st | −1p, +7, −15q, −19q, +22q | −1p/19q | none | Yes | 104 | 134 | Alive |
| O GIII* 9 | 34M | 4 th | −1p, −4, −10q, −13q, −14q, −15qcen-21, +15q24-ter, −19q | −1p/19q | none | Yes | 9 | 111 | Alive |
| O GIII* 11 | 36F | 1 st | −1p, −19q | −1p/19q | none | Yes | 17 | 26 | Alive |
| O GIII* 6 | 36M | 2 nd | −1p, −17p, −18q, −19q | −1p/19q | none | No | 7 | 34 | Alive |
| O GIII* 18 | 39M | 2 nd | −1p, −14q, −19q, +21q | −1p/19q | none | No | 6 | 69 | Alive |
| O GIII* 16 | 40F | 2 nd | −1p, +11, −14, −19q | −1p/19q | none | No | 48 | 102 | Alive |
| O GIII* 19 | 57M | 2 nd | −1p, −14q13-24, −19q | −1p/19q | none | Yes | 12 | 85 | Alive |
| O GIII* 19 | 58M | 3 rd | −1p, +7, −14q21-24.3, −15q15-22.1, −19q | −1p/19q | none | Yes | 6 | 85 | Alive |
| O GIII | 68F | 1 st | −1p, +2, −3p, +3q, −4, +5, +7, +8, +9q, 13q, +14q, +17, −19q | −1p/19q | none | No | 21 | 21 | Alive |
The genetic type indicates detected the CNAs which are regarded as a favorable CNA (–1p/19q) or unfavorable CNAs (+7q, +8q, −9p, and/or −11p). A repeated number denoted by an asterisk indicates ta single patient who underwent multiple surgeries. Abbreviations: NA, not available.