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. 2015 Nov 11;10(11):e0142205. doi: 10.1371/journal.pone.0142205

Table 3. Rate of AECOPD events before and after Ig treatment classified by stage of COPD based on GOLD criteria, presence or absence of radiographic bronchiectasis, or baseline IgG level.

Before (AECOPD events/patient-year) After (AECOPD events/patient-year)
Stage of COPD
Moderate COPD (n = 7) 5.14 ± 2.85 0.86 ± 1.13
Severe / very severe COPD 4.14 ± 2.95 0.43 ± 0.5
Presence of bronchiectasis
No bronchiectasis (n = 6) 4.00 ± 2.83 0.83 ± 1.07
With bronchiectasis 5.13 ± 2.93 0.50 ± 0.71
Baseline IgG level
IgG ≥ 5.9 g/L (n = 7) 4.29 ± 3.33 0.29 ± 0.45
IgG < 5.9 g/L 5.00 ± 2.45 1.00 ± 1.07

IgG = 5.9 g/L is the median IgG in our case series.