Fig 10. A. Total number of conserved and predicted signalling pathways in each metastatic melanoma stage. B. Top 20 conserved signalling pathways of CM with their gene count in both the metastatic stages. C. Comparison of R-score trend observed for the conserved signalling pathways. It can be observed that conserved signalling pathways possess similar R-score across mutually exclusive datasets. D. Peaks representing IM density of conserved signalling pathways, follows similar pattern in both the metastatic melanoma stages.