Table 2. Pooled HCV seroprevalence overall and stratified by migration status, region of origin, and age.
Abbreviations: CI, confidence interval.
| N studies | N subjects | Seroprevalence % (95% CI) | I2% (95% CI) | |
|---|---|---|---|---|
| Overall | 50 | 38 635 | 1.9 (1.4, 2.7) | 96.1 (95.5, 96.7) |
| Overall (without children) | 41 | 36 183 | 2.2 (1.6, 3.2) | 96.7 (96.1, 97.2) |
| Age a | ||||
| ≤ 18 years | 11 | 3767 | 0.8 (0.4, 1.6) | 63.8 (30.8, 81.1) |
| 19–29 years | 15 | 9172 | 2.0 (1.3, 3.1) | 88.5 (82.7, 92.4) |
| ≥ 30 years | 9 | 6370 | 5.6 (3.7, 8.5) | 93.6 (89.9, 95.9) |
| Population category | ||||
| Children b | 9 | 2452 | 0.6 (0.3, 1.3) | 16.1 (0, 58.2) |
| Pregnant Women | 8 | 8347 | 2.0 (1.3, 3.1) | 85.5 (73.3, 92.1) |
| General Population | 33 | 27838 | 2.3 (1.6, 3.5) | 96.8 (96.2, 97.3) |
| Migrant status | ||||
| Immigrants | 29 | 17 800 | 2.3 (1.5, 3.5) | 95.9 (94.9, 96.7) |
| Refugees | 11 | 5186 | 1.3 (0.8, 2.2) | 69.4 (42.9, 83.6) |
| Other c | 10 | 15 649 | 2.2 (1.2, 3.9) | 95.8 (93.9, 97.1) |
| Region of origin | ||||
| Latin America & Caribbean | 13 | 5240 | 0.7 (0.5, 1.1) | 19.6 (0, 57.6) |
| Eastern Europe & Central Asia | 25 | 7505 | 2.2 (1.3, 3.8) | 89.3 (85.5, 92.1) |
| Middle East & North Africa | 11 | 2681 | 1.4 (0.8, 2.4) | 38.3 (0, 69.6) |
| Sub-Saharan Africa | 15 | 4446 | 4.4 (2.6, 7.4) | 91.5 (87.7, 94.2) |
| South Asia | 4 | 354 | 4.8 (0.9, 21.3) | 69.7 (12.7, 89.5) |
| East Asia & Pacific | 7 | 1007 | 1.6 (0.9, 2.7) | 0 (0, 53.5) |
| Combined Africa | 9 | 2095 | 4.6 (2.7, 7.7) | 79.2 (61.1, 88.9) |
| Combined Asia | 10 | 1107 | 3.8 (2.3, 6.3) | 39.4 (0, 71.1) |
| Setting for screening | ||||
| Adopted kids | 7 | 1350 | 0.7 (0.4, 1.5) | 0 (0, 0.6) |
| Migrant screening | 15 | 14 060 | 1.3 (0.9, 2.0) | 80.5 (68.7, 87.8) |
| General clinics | 28 | 23 225 | 2.9 (1.9, 4.2) | 96.7 (96.0, 97.3) |
| Decade of publication | ||||
| 1990–1999 | 14 | 7655 | 2.8 (1.6, 4.7) | 93.2 (90.3, 95.3) |
| 2000–2009 | 27 | 22518 | 1.6 (1.0, 2.3) | 90.9 (88.0, 93.1) |
| 2010–2013 | 9 | 8462 | 2.4 (1.3, 4.6) | 96.8 (95.4, 97.8) |
| EIA test generation | ||||
| 1st generation | 1 | 88 | 2.3 (0.6, 8.6) | - |
| 2nd generation | 12 | 6632 | 2.2 (1.4, 3.5) | 86.9 (78.9, 91.8) |
| 3rd generation | 37 | 31915 | 1.8 (1.2, 2.8) | 96.8 (96.2, 97.3) |
a Only 35 of the 50 studies provided information regarding age of the study population and age groups were classified by mean or median age of the study population.
b Population Category included all studies: Children (all subjects were <18 years), pregnant women, general population (mixed ages including some children).
c The ‘Other’ subgroup includes studies where results were not stratified by migrant status.