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. 2015 Nov 11;10(11):e0142067. doi: 10.1371/journal.pone.0142067

Fig 1. ONC yields progressive RGC degeneration, diffusely distributed throughout the retina.

Fig 1

(A) ONC-induced RGC death in the ONC eye (OS) is progressive between 4 and 21 dpi. (B) Representative images of naive or injured retinas in which RGCs are visualized through Brn3a IHC. Right panels show isodensity maps with the numbers indicating percentages of surviving RGCs compared to naive. Scale bars left: 500 μm, middle: 50 μm. Key: ONC, optic nerve crush; RGC, retinal ganglion cell; IHC, immunohistochemistry; dpi, days post-injury; OS, oculus sinister; OD, oculus dexter.