Table 1.
Baseline characteristics of hypertensive subjects categorized by statin use on high and low sodium diets.
| n=317 | No Statin Group (85%) | Statin Group (15%) | p value |
|---|---|---|---|
| Age (years) | 49.1 ± 7.1 | 53.9 ± 6.6 | 0.001 |
| Female (%) | 43.5 | 46.3 | 0.76 |
| Body Mass Index (kg/m2) | 28.6 ± 4.4 | 30.8 ± 4.2 | 0.001 |
| Systolic Blood Pressure on HS | 146.6 ± 18.6 | 141.0 ± 18.4 | 0.07 |
| Systolic Blood Pressure on LS | 131.4 ± 16.1 | 127.9 ± 14.4 | 0.16 |
| Urinary sodium on HS* diet (24h mmol) | 232.9 ± 68.4 | 228.6 ± 70.2 | 0.70 |
| Urinary sodium on LS* diet (24h mmol) | 13.9 ± 7.6 | 14.7 ± 7.8 | 0.54 |
| HS plasma potassium (mmol/L) | 4.15 ± 0.3 | 4.14 ± 0.3 | 0.87 |
| LS plasma potassium (mmol/L) | 4.17 ± 0.3 | 4.12 ± 0.3 | 0.32 |
| HS Plasma renin activity (ng/mL*h) | 0.51 ± 0.4 | 0.35 ± 0.3 | 0.18 |
| LS Plasma renin activity (ng/mL*h) | 2.49 ± 2.8 | 1.91 ± 1.7 | 0.34 |
| HS LDL Cholesterol mmol/L | 3.21 ± 0.9 | 3.16 ± 1.1 | 0.80 |
Data reported as mean ± SD, except as noted. HS indicates high sodium; LS, low sodium