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. Author manuscript; available in PMC: 2016 Nov 10.
Published in final edited form as: Circulation. 2015 Oct 2;132(19):1825–1833. doi: 10.1161/CIRCULATIONAHA.115.016759

Table 4.

Effect of statin use on systolic blood pressure, salt sensitivity and pulse pressure.

Blood Pressure (BP) analysis 1070 observations Model 2
Statin effect (Adjusted β) p value
Systolic BP in all 4 measurements (HSbase,HSstim,LSbase,LSstim)* mmHg −5.57 p =0.001
Systolic BP on HS (HSbase,HSstim) mmHg −6.03 p =0.001
Systolic BP on LS (LSbase,LSstim) mmHg −5.46 p = 0.001
Salt sensitivity of BP (Systolic HSbase – Systolic LSbase) mmHg −5.85 p <0.001
Pulse pressure in all 4 measurements (Systolic-Diastolic) mmHg −2.95 p =0.004
*

High sodium (HS) baseline (base), HS Angiotensin II stimulation (stim), Low sodium (LS)

Mixed Model adjusted by age, BMI, gender, urinary sodium (LS, HS), race, site and randomization order.