Table III.
Frequency of positive results as measured by serological IgE antibody assays (ImmunoCAP) and ISAC analysis on the sera positive to extracts in adult and pediatric patients with EoE.
| ISAC molecular allergen |
|||||||
|---|---|---|---|---|---|---|---|
| Allergen extract | IgE Ab* (n=89) | ISAC† (n=90) | Number of molecules | 1st | 2nd | 3rd | 4th |
| egg | 19/89 | 4/19 | (4)‡ | Gal d 1 (0/19)§ | Gal d 2 (0/19) | Gal d 3 (2/19) | Gal d 5 (2/19) |
| milk | 42/89 | 4/42 | (5) | Bos d 4 (2/42) | Bos d 5 (1/42) | Bos d 6 (1/42) | Bos d 8 (0/42) |
| wheat | 39/89 | 0/39 | (3) | Tri a 14 (0/39) | Tri a 19 (0/39) | Tri a A_T (0/39) | - |
| soy | 28/89 | 8/28 | (3) | Gly m 4 (2/28) | Gly m 5 (5/28) | Gly m 6 (5/28) | - |
| peanut | 33/89 | 11/33 | (5) | Ara h 1 (2/33) | Ara h 2 (2/33) | Ara h 8 (4/33) | Ara h 9 (3/33) |
| dust mite | 26/87 | 18/26 | (5) | group 1 (12/18) | group 2 (11/18) | Der p 10 (5/18) | Blo t 5 (4/18) |
| cat | 31/87 | 30/31 | (3) | Fel d 1 (27/30) | Fel d 4 (10/30) | Fel d 2 (5/30) | - |
| dog | 17/46 | 9/17 | (4) | Can f 1 (8/17) | Can f 2 (6/17) | Can f 3 (2/17) | Can f 5 (10/19) |
| mold | 15/47 | 13/15 | (6) | Alt a 1 (13/15) | Asp f 1 (0/15) | Cla h 8 (1/15) | - |
| tree | 25/87 | 19/25 | (3) | Bet v 1 (15/19) | Bet v 2 (8/19) | Bet v 4 (0/12) | - |
| grass | 33/87 | 30/33 | (9) | Phl p 1 (20/30) | Phl p 4 (12/30) | Phl p 12 (9/30) | Cyn d 1 (24/30) |
| ragweed | 35/87 | 21/35 | (1) | Amb a 1 (21/35) | - | - | - |
*
Results are given as number positive/number of samples tested by ImmunoCAP and ISAC.
†
Results are given as number of sera positive to any ISAC molecule/number positive to allergen extract by ImmunoCAP.
‡
Number of molecules tested for each allergen by ISAC
§
Results in parentheses are given as number positive to the specific ISAC molecule/number positive to whole allergen extract.