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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Dev Biol. 2015 Aug 20;407(1):26–39. doi: 10.1016/j.ydbio.2015.08.010

Figure 6. Loss of Gbx2 causes abnormal cell proliferation in the thalamus.

Figure 6

(A-F) Immunofluorescence on coronal sections of control and Gbx2-KO thalamus at E13.5 following BrdU chase or pulse labeling as indicated. Dashed lines demarcate the boundary between the thalamus and the epithalamus; arrowheads indicate the three stripes of BrdU+ cells parallel to the ventricular surface; the asterisk shows the abnormal curvature of the outer band of BrdU+ cells in the dorsal-most region of the thalamus due to the loss of Gbx2. (G-I) Histogram representation of quantification of proliferating and newly generated postmitotic cells. Asterisks indicate statistical significance (p<0.05, Student's t-test).