Table 2.

Comparison of individual SNOT-22 elements between H-AS and AT groups.

Comparison of individual SNOT-22 item scores between CRS patient with history of aspirin sensitivity (H-AS) and those without (AT). Individual symptoms that are still significant after correction for multiple comparisons are shown in bold. Bonferroni correction was applied to adjust for p-value. P values less than 0.05 considered significant after correction.

Item	Description	H-AS Mean ± SEM	AT Mean ± SEM	P-value	Corrected
1	Need to blow nose	3.7 ± 0.3	2.3 ± 0.2	<0.001	<0.001
2	Sneezing	2.2 ± 0.3	1.5 ± 0.2	0.03	0.66
3	Runny nose	3.6 ± 0.3	2.1 ± 0.2	<0.001	<0.006
4	Cough	2.0 ± 0.3	1.7 ± 0.2	0.34
5	Post nasal discharge	3.2 ± 0.3	2.4 ± 0.2	0.03	0.66
6	Thick nasal discharge	3.6 ± 0.4	2.2 ± 0.2	<0.001	0.01
7	Ear fullness	2.6 ± 0.4	1.5 ± 0.2	0.008	0.17
8	Dizziness	1.4 ± 0.3	0.9 ± 0.2	0.13
9	Ear pain/pressure	1.4 ± 0.2	0.5 ± 0.1	0.002	0.05
10	Facial pain/pressure	2.2 ± 0.3	1.8 ± 0.2	0.33
11	Difficulty falling asleep	2.0 ± 0.3	1.4 ± 0.2	0.13
12	Waking up at night	2.5 ± 0.3	2.0 ± 0.2	0.13
13	Waking up tired	2.8 ± 0.3	1.8 ± 0.2	0.01	0.22
14	Lack of good night’s sleep	3.0 ± 0.3	2.2 ± 0.2	0.03	0.66
15	Fatigue during the day	2.7 ± 0.4	2.1 ± 0.2	0.10
16	Reduced productivity	2.3 ± 0.3	1.7 ± 0.2	0.14
17	Reduced concentration	2.3 ± 0.4	1.8 ± 0.2	0.21
18	Frustrated/restless/irritable	2.3 ± 0.3	1.6 ± 0.2	0.08
19	Sad	1.1 ± 0.2	0.5 ± 0.1	0.01	0.22
20	Embarrassed	1.3 ± 0.3	0.5 ± 0.1	0.004	0.08
21	Sense of taste/smell	4.6 ± 0.4	2.9 ± 0.2	<0.001	<0.002
22	Blockage/congestion of nose	4.0 ± 0.3	3.0 ± 0.2	0.008	0.17

H-AS: History of aspirin sensitivity, AT: No history of aspirin sensitivity. P<0.05 considered significant.