Table 4.
L-BMAA concentrations (μg/g) in brains and livers of mice as detected by LC/MS/MS chromatography. Each value is the mean of three replicates ± standard deviation. BW: body weight; F: female; M: male. A, B, and E: mice treated (0.03, 0.3, and 3 mg/g BW) groups.
| L-BMAA dose (mg/g BW) | Gender | L-BMAA (µg/g) in brain | L-BMAA (µg/g) in liver |
|---|---|---|---|
| Control (0) | F | 0.00 ± 0.00 | 0.00 ± 0.00 |
| M | 0.00 ± 0.00 | 0.00 ± 0.00 | |
|
| |||
| (A) 0.03 | F | 1.61 ± 0.41 | 1.12 ± 0.10 |
| M | 3.34 ± 0.52 | 1.53 ± 0.21 | |
|
| |||
| (B) 0.30 | F | 4.69 ± 0.34 | 2.64 ± 0.28 |
| M | 8.41 ± 0.56 | 3.85 ± 0.22 | |
|
| |||
| (E) 3.00 | F | 21.79 ± 0.92 | 11.94 ± 0.64 |
| M | 32.62 ± 0.99 | 15.59 ± 0.57 | |