Table 4. Effect of soy bread and regular diet on serum lipids and blood pressure*.
Variables | First phase (n = 30) |
Second phase (n = 30) |
Mean change difference† | p value‡ | ||
---|---|---|---|---|---|---|
Week 0 | Week 6 | Week 9 | Week 15 | |||
TC, mg/dL | ||||||
SBD§ | 170.3 ± 28.3 | 162.1 ± 35.3 | 179.4 ± 27.1 | 171.7 ± 22.7 | 3.1 ± 13.8 | 0.23 |
RD∥ | 183.3 ± 24.8 | 177.0 ± 28.5 | 159.3 ± 21.8 | 155.8 ± 22.7 | ||
TG, mg/dL | ||||||
SBD | 111.9 ± 38.9 | 101.0 ± 42.4 | 112.9 ± 54.3 | 106.7 ± 50.4 | 5.3 ± 16.8 | 0.01 |
RD | 108.7 ± 45.5 | 105.3 ± 46.8 | 104.6 ± 33.4 | 101.6 ± 39.1 | ||
LDL-C, mg/dL | ||||||
SBD | 106.4 ± 23.8 | 99.2 ± 28.7 | 115.3 ± 25.5 | 108.4 ± 22.5 | 2.2 ± 10.8 | 0.27 |
RD | 119.4 ± 21.9 | 113.2 ± 24.2 | 98.0 ± 18.7 | 94.6 ± 19.6 | ||
HDL-C, mg/dL | ||||||
SBD | 41.5 ± 7.4 | 42.7 ± 7.2 | 41.5 ± 9.2 | 42.1 ± 9.3 | 0.0 ± 2.5 | 0.90 |
RD | 42.1 ± 8.6 | 42.8 ± 8.4 | 40.3 ± 8.0 | 41.2 ± 7.5 | ||
SBP, mmHg | ||||||
SBD | 113.6 ± 8.3 | 107.9 ± 7.6 | 114.5 ± 7.3 | 108.1 ± 6.5 | 3.6 ± 5.9 | 0.90 |
RD | 113.0 ± 5.9 | 110.1 ± 7.4 | 113.3 ± 5.7 | 11.3 ± 6.3 | ||
DBP, mmHg | ||||||
SBD | 75.2 ± 5.8 | 70.8 ± 6.4 | 77.6 ± 4.8 | 74.6 ± 6.6 | 2.0 ± 5.7¶ | 0.06 |
RD | 78.3 ± 4.9 | 75.5 ± 7.6 | 73.9 ± 6.7 | 73.4 ± 6.04 |
TC: total cholesterol, TG: triglycerides, LDL-C: low density lipoprotein cholesterol, HDL-C: high density lipoprotein cholesterol, SBP: systolic blood pressure, DBP: diastolic blood pressure, SBD: soy bread diet, RD: regular diet.
*All values are showed in mean ± SD; †Mean change differences of variable = mean differences in soy bread diet - mean differences in regular diet; ‡p values for mean change differences between two groups (Paired t-test); §All subjects in this group received a weight loss diet and were also asked to replace 120 g of their usual bread intake with identical amount of soy bread; ∥All participant were on their regular diet; subjects were asked not to consume soy products. ¶Marginally significant difference for DBP between SBD and RD (p = 0.06).