Table 2.
ABCG2 and SLC2A9 single nucleotide polymorphisms
| Gene | Polymorphism (dbSNP no) | Polymorphism (HGVS nomenclature) | Genotype frequency in patients with gout (%) | Odds ratio |
|---|---|---|---|---|
| ABCG2 | rs2231142 | c.421C>A | AC (46.7) | 3.32a |
| ABCG2 | ∙ | c.871+386A>G | AA (95.4) | |
| SLC2A9 | rs6449213 | c.410+4190A>G | AA (98.2) | |
| SLC2A9 | ∙ | c.410+4124C>T | CC (98.2) | |
| SLC2A9 | ∙ | c.410+4242G>A | GG (99.1) | |
| SLC2A9 | rs16890979 | c.844A>G | AA (100) | |
| SLC2A9 | ∙ | c.881A>G | AA (47.7) | 1.54a |
| SLC2A9 | ∙ | c.1002 + 78G>A | GG (55.9) | 1.64a |
| SLC2A9 | ∙ | c.813-18A>G | AA (99.1) |
dbSNP, single nucleotide polymorphism database; HGVS, Human Genome Variation Society.
a
p < 0.05.