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IL-4−/−IL-13−/− mice exposed to Schistosoma mansoni eggs have suppressed Th1 and Th17 responses. (A–C) Flow cytometric histograms of CD3+CD4+ populations from digested whole-lung tissue, individually gated for IFN-γ (A), IL-17A (B), and IL-17F (C) in intraperitoneal and intravenous (IP/IV) egg–exposed IL-4−/−IL-13−/− and wild-type (WT) mice (flow studies repeated at least three times).
