Table 1.
Discovery and internal validation cohort demographic details.
Clinical groups | n (M/F) | Mean age years [SD] | Mean education years [SD] | % APOE ϵ4 |
---|---|---|---|---|
Normal control (NC) | ||||
Discovery | 53 (18/35) | 81.6 [3.6] | 15.7 [2.3] | 24.6 |
Internal validation | 20 (9/11) | 81.4 [3.3] | 15.1 [2.5] | 20 |
Converterpre | ||||
Discovery | 18 (8/10) | 80.7 [2.3] | 15.3 [3.1] | 16.7 |
Internal validation | 10 (4/6) | 79.3 [5.5] | 14.5 [1.8] | 20 |
Total discovery | 71 (26/45) | 81.8 [3.0] | 15.5 [2.7] | 20.7 |
Total internal validation | 30 (13/17) | 80.9 [4.4] | 14.8 [2.2] | 20.0 |
n, number of subjects; F, female subjects; M, male subjects; SD, standard deviation; % APOE ϵ4, percent having at least a single APOE ϵ4 allele.
Gender, age, education, and APOE ϵ4 status were not significantly different (Chi-square p > 0.05) between discovery and internal validation groups.