. Author manuscript; available in PMC: 2016 Oct 1.

Published in final edited form as: Neurobiol Dis. 2015 Jun 30;82:281–288. doi: 10.1016/j.nbd.2015.06.017

Table 1.

Time course of UBQLN2 and ubiquitin recruitment to HTT neuronal nuclear inclusions in HD-KI (Q200) mice

	Hippocampus/cortex/striatum			Cerebellum
Staining	20wks	45wks	75wks	20wks	45wks	75wks
Anti-HTT	-	++	+++	-	++	+++
Anti-UBQLN2	-	++	+++	-	-	++
Anti-Ubiquitin	-	++	+++	-	++	+++

‘-’ diffuse nuclear staining only; ‘++’ obvious immunoreactive nuclear inclusions; ‘+++’ increasing numbers of immunoreactive nuclear inclusions.