Table 1.
Demographics of subjects evaluated to compare detection of IFN-γ responses by group M and clade-based consensus peptides.
| Parameter; median (IQR) | HIV clades (number of subjects) |
|||
|---|---|---|---|---|
| Clade A1 (14) | Clade D (10) | Overall (24) | P value | |
| Gender ratio (male/female) | 3/11 | 2/8 | 5/19 | 1.0 |
| Age (years) | 39 (36–44) | 39 (31–58) | 39 (35–45) | 0.97 |
| Plasma viral load (RNA copies/ml) | 21950 (1900–117800) | 12150 (2923–30950) | 12700 (2748–41700) | 0.785 |
| CD4+ T-cell counts (cells/μl) | 571 (499–787) | 645 (569–822) | 616 (514–794) | 0.4 |
| WHO clinical stage [%]: (I, II and III) | 14, 64 and 21 | 10, 40 and 50 | 33, 54 and 13 | 0.34 |
| Genetic distance from ConM (%) | 8.9 (8.2–9.7) | 9.0 (8.3–1.0) | 9.0 (8.3–1.0) | 0.55 |
| Genetic distance from ConA (%) | 5.3 (4.4–6.5) | 13.6 (13.2–14.3) | 6.6 (5.2–13.3) | 0.0001a |
| Genetic distance from ConD (%) | 13 (12–13) | 5.6 (5.2–5.8) | 11.0 (5.8–13.0) | 0.0006a |
a
Mann–Whitney test.