Table 2.
Demographics of subjects evaluated to compare ability of group M and clade-based consensus peptides to detect of HIV-specific functional T-cell subsets.
| Parameter; median (IQR) | Consensus peptide set (number of subjects evaluated) |
P value | ||
|---|---|---|---|---|
| ConM (29) | ConA (12) | ConD (17) | ||
| Gender ratio (male/female) | 8/21 | 7/5 | 4/13 | 0.1 |
| Age (years) | 36 (29–43) | 38 (33–44) | 38 (34–44) | 0.83 |
| Infecting clade (A1/D) | 13/16 | 6/6 | 8/9 | 0.95 |
| Plasma viral load (RNA copies/ml) | 12,700 (4340–97,300) | 14,200 (5673–290,300) | 11,600 (2285–27,100) | 0.57 |
| CD4+ T-cell counts (cells/μl) | 551 (496–714) | 566 (514–655) | 650 (530–943) | 0.19 |
| WHO clinical stage [%]: (I, II and III) | 17, 69 and 14 | 25, 58 and 17 | 35, 53 and 12 | 0.73 |
| Genetic distance from ConM (%) | 9.3 (8.5–10.0) | 9.3 (8.4–12.0) | 8.9 (8.3–10.0) | 0.84 |