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. 2015 Nov 10;6(6):694–702. doi: 10.3945/an.115.009423

FIGURE 3.

FIGURE 3

Effects of the Western diet and 20–22-carbon ω-3 PUFAs on the prevention of NASH Ldlr−/− mice. The size of the arrow indicates effect size. No effect indicates no changes from WD + olive oil-fed mice. Olive oil was added to the WD to keep all diets isocaloric. ALT, alanine aminotransferase; AST, aspartate aminotransferase; CD14, CD14 molecule gene; CD68, CD68 molecule gene; Col1A, collagen 1A1 gene; Ldlr−/−, global ablation of the LDL receptor gene; MCP1, monocyte chemoattractant protein-1; NASH, nonalcoholic steatohepatitis; NOX2, NADPH oxidase 2 gene; P67Phox, 67 kDa neutrophil cytosolic factor 2; TLR4, toll-like receptor 4 gene; WD, Western diet.