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US adipose tissue LA concentration, 1959–2008. Increase in adipose tissue LA concentration over time across all subcutaneous sites (R2 = 0.83; P < 0.001) (A). Increase in adipose tissue LA concentration over time, buttocks and abdominal subcutaneous only (R2 = 0.86; P < 0.001) (B). LA, linoleic acid.
