Table 2.
Odds ratios and 95% confidence intervals for the association between hyperglycemia during pregnancy and prenatal depression
| Glucose assessment | % with depressive symptoms / number of women | Model 11 | Model 22 |
|---|---|---|---|
| Continuous4 | |||
| Per SD changes (SD=27 mg/dL) | 9.6 / 2112 | 1.31 (1.12, 1.52) | 1.25 (1.07, 1.48) |
| Glucose categories (mg/dL)3 | |||
| 55–90 | 7.4 / 385 | 1.00 (Reference) | 1.00 (Reference) |
| 91–100 | 9.1 / 316 | 1.29 (0.71, 2.35) | 1.30 (0.70, 2.41) |
| 101–120 | 8.4 / 649 | 1.25 (0.73, 2.15) | 1.21 (0.69, 2.12) |
| 121–140 | 10.8 / 388 | 1.74 (0.99, 3.06) | 1.68 (0.93, 3.02) |
| 141–230 | 13.5 / 374 | 2.41 (1.39, 4.18) | 2.17 (1.21, 3.88) |
| p for trend4 | 0.0005 | 0.0066 | |
| GDM status | |||
| Normal | 8.8 / 1738 | 1.00 (Reference) | 1.00 (Reference) |
| IHG | 14.4 / 179 | 2.02 (1.25, 3.29) | 1.86 (1.12, 3.09) |
| IGT | 11.5 / 65 | 1.45 (0.61, 3.45) | 1.44 (0.60, 3.46) |
| GDM | 12.7 /130 | 1.69 (0.88, 3.23) | 1.47 (0.74, 2.93) |
1
Adjusted for age
2
Model 1 plus race/ethnicity, education, nativity, parity, marital status, household income, pre-pregnancy BMI and pre-pregnancy physical activity
3
Based on glucose levels from glucose challenge test
4
p for trend was calculated using continuous glucose levels as a linear term