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. 2015 Aug 17;5:13225. doi: 10.1038/srep13225

Figure 2. The effects of prenatal caffeine on L-type calcium channels (LTCCs) in mesenteric arteries and myocytes.

Figure 2

(A) Nifedipine (Nif) concentration-dependently blunted KCl-induced vasoconstrictions (n = 7 each group). *P < 0.05. (B,C) Representative curve showing whole cell inward currents in absence (top) and presence (bottom) of nifedipine (10−6 mol/L) in the control (B) and caffeine (C) group. (D) Current-voltage (I-V) relationships for LTCC currents in the offspring (n = 24 cells, 7 animals/each group). (E) Representative blots for α1c-subunit of LTCCs in offspring MA. (F) The LTCC α1c expression normalized to the control (n = 6 each group). Gels were treated under the same experimental conditions with the control and experimental groups treated together.