Table 1. Echocardiographic results at 7-day post MI.
| Parameters | WT/Sham(n=6) | HDC−/−/Sham(n=5) | WT/MI(n=6) | HDC−/−/MI(n=6) | HDC−/−+His/MI(n=7) |
|---|---|---|---|---|---|
| LVEF(%) | 71.09 ± 2.59 | 68.49 ± 3.82 | 36.8 ± 4.35*** | 24.5 ± 2.49* | 34.61 ± 3.59# |
| LVFS(%) | 39.89 ± 2.06 | 37.73 ± 3.03 | 17.77 ± 2.4*** | 11.24 ± 1.2* | 16.52 ± 1.95# |
| LVEDd(mm) | 3.51 ± 0.11 | 3.42 ± 0.34 | 4.36 ± 0.1*** | 4.44 ± 0.2 | 4.37 ± 0.18 |
| LVESd(mm) | 2.22 ± 0.17 | 2.15 ± 0.26 | 3.59 ± 0.15*** | 3.95 ± 0.2 | 3.66 ± 0.21 |
| LVAWd(mm) | 0.82 ± 0.11 | 1.03 ± 0.18 | 0.73 ± 0.08 | 0.76 ± 0.11 | 0.81 ± 0.07 |
| LVAWs(mm) | 1.27 ± 0.11 | 1.4 ± 0.14 | 0.89 ± 0.15 | 0.82 ± 0.08 | 1.02 ± 0.11 |
His: histamine, 4 mg/kg/d; LVEF: left ventricular ejection fraction; LVFS: left ventricular fraction shortening; LVEDd: left ventricular end-diastolic diameter; LVESd: left ventricular end-systolic diameter; LVAWd: left ventricular diastolic anterior wall thickness; LVAWs: left ventricular systolic anterior wall thickness.
***P < 0.001 vs WT/Sham; *P < 0.05 vs WT/MI; #P < 0.05 vs HDC−/−/MI.