Table 1. Clinicopathologic variables and the expression status of DBC1 and androgen receptor in 35 osteosarcoma patients.
Characteristics | N | DBC1 |
AR |
|||
positive | p | positive | p | |||
Age, yr | <30 | 25 | 11 (44%) | 0.392 | 12 (48%) | 0.915 |
≥30 | 10 | 6 (60%) | 5 (50%) | |||
Sex | Female | 10 | 1 (10%) | 0.004 | 3 (30%) | 0.164 |
Male | 25 | 16 (64%) | 14 (56%) | |||
Tumor size, cm | ≤8 | 17 | 5 (29%) | 0.028 | 8 (47%) | 0.862 |
>8 | 18 | 12 (67%) | 9 (50%) | |||
Stage | I | 11 | 2 (18%) | 0.035 | 1 (9%) | 0.005 |
II | 19 | 11 (58%) | 12 (63%) | |||
III–IV | 5 | 4 (80%) | 4 (80%) | |||
Distant metastasis | Absence | 30 | 13 (43%) | 0.129 | 13 (43%) | 0.129 |
Presence | 5 | 4 (80%) | 4 (80%) | |||
Histological grade | Low | 11 | 2 (18%) | 0.015 | 1 (9%) | 0.002 |
High | 24 | 15 (63%) | 16 (67%) | |||
Histologic type | Conventional | 31 | 16 (52%) | 0.316 | 14 (45%) | 0.261 |
Non-conventional | 4 | 1 (25%) | 3 (75%) | |||
AR | Negative | 18 | 4 (22%) | 0.001 | ||
Positive | 17 | 13 (76%) |
DBC1, deleted in breast cancer 1; AR, androgen receptor.