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. 2015 Sep 8;5:13829. doi: 10.1038/srep13829

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Copyright © 2015, Macmillan Publishers Limited

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Modelled structures were performed with the crystal structures of XylE bound to D-glucose (a) and GLUT1 in an inward-open state (b) as the template, respectively. The N and C domains are coloured grey and tan, respectively, and intracellular helices connecting these two domains are coloured yellow. D-glucose is indicated by the spheres. (c) Putative helix-packing arrangement viewed from the extracellular surface. (d) Putative stacking of TMs 6 and 1 (left) and TMs 3 and 4 (right). Residues with putative interactions are shown as spheres. Phe 50, Ile 115 and Pro 214 are represented in magenta.