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. 2015 Dec;62:129–137. doi: 10.1016/j.psyneuen.2015.08.005

Table 4.

Mediation Analysis.

β
% Mediation model
X Y M c c Attenuation F (df) Lower CI Upper CI
STARTa gfR gMD −.34d −.29d 14.71 5.53 (2,67) −.2573 −.0071
STARTa gfR WMHb −.28c −.28c 0.00 3.20 (2,74) −.0748 .1030
STARTa SpeedR gMD −.42e −.36e 14.29 9.70 (2,67) −.3147 −.0254
STARTa SpeedR WMHb −.35d −.32d 8.57 6.53 (2,74) −.2665 −.0036
STARTa MemoryR gMD −.42e −.36d 14.29 8.40 (2,67) −.3178 −.0047
STARTa MemoryR WMHb −.35d −.31d 11.43 6.67 (2,74) −.2648 −.0005
ENDa gfR WMHb −.36d −.35d 2.78 5.60 (2,77) −.0890 .0562
ENDa SpeedR WMHb −.35d −.31d 11.43 7.08 (2,77) −.2203 −.0074
ENDa MemoryR WMHb −.36d −.33d 8.33 7.32 (2,76) −.2286 −.0013

X: independent variable, Y: outcome variable, M: mediator, c: path from X to Y (listwise, may differ slightly from pairwise associations reported in Table 2), c’: path from X to Y accounting for M. Bold type face indicates significant mediation effect (confidence intervals do not include 0; Preacher and Hayes, 2008). START: cortisol levels at the start of cognitive testing, END: cortisol levels at the end of cognitive testing, gf: general cognitive ability, speed: speed of processing, memory: memory ability, R: variable is a residual, corrected for age 11 cognitive ability. All tests of mediation are one-tailed and bias-corrected.

a

Log transformed.

b

Square root transformed.

c

< .05.

d

p < .01.

e

< .001.