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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: N Engl J Med. 2015 Oct;373(14):1340–1349. doi: 10.1056/NEJMsa1502403

Figure 3. Nicotine Dependence According to the Nicotine Content of Cigarettes.

Figure 3

Panel A shows total scores on the Wisconsin Inventory of Smoking Dependence Motives (score range, 11 to 77, with higher values indicating greater dependence), which is a multifactorial scale of nicotine dependence. Panel B shows total scores on the Fagerström Test for Nicotine Dependence, with the item concerning number of cigarettes smoked per day excluded (score range after exclusion of that item, 0 to 7, with higher values indicating greater dependence). All analyses were adjusted for the baseline score. An asterisk indicates P≤0.002 for the comparison at week 6 with cigarettes containing 15.8 mg of nicotine per gram.