Table 3.
Characteristics of vitamin D-deficient and vitamin D-sufficient hypertensive patients from the MAGIC study.
| <20 ng/mL 25(OH)D | ≥20 ng/mL 25(OH)D | P for Comparison | |
|---|---|---|---|
| No. | 86 | 79 | |
| 25(OH)D (ng/mL) | 13.4 ± 4.3 | 28.7 ± 8.1 | |
| Males | 60 (69.8%) | 53 (67.1%) | 0.65 |
| Age (years) | 47.1 ± 9.5 | 46.3 ± 9.5 | 0.59 |
| BMI (kg/m2) | 26.5 ± 3.7 | 25.8 ± 2.9 | 0.18 |
| eGFR (mL/min/m2) | 92.7 ± 14.5 | 89.4 ± 15.9 | 0.17 |
| Active smokers | 18 (20.9)% | 19 (24.1%) | 0.58 |
| SBP | 154.9 ± 13.2 | 152.7 ± 10.2 | 0.22 |
| 24-h SBP (mm/Hg) | 141.3 ± 15.6 | 140.2 ± 12.2 | 0.62 |
| LDL (mg/dL) | 145.6 ± 35.8 | 126.9 ± 50.7 | 0.01 |
| Fasting glucose (mg/dL) | 92.9 ±11.0 | 89.8 ± 11.7 | 0.09 |
| hsCRP (mg/L) | 0.24 ± 0.31 | 0.21 ± 0.27 | 0.49 |
| Aldosterone (pg/mL) | 104.9 ± 58.0 | 121.1 ± 70.1 | 0.14 |
| Season | |||
| November–April | 63 (73.3%) | 32 (40.5%) | |
| May–October | 23 (26.7%) | 47 (59.5%) | <0.0001 |
| PTH (pg/mL) | 8.7 ± 6.4 | 8.8 ± 6.1 | 0.87 |
| IGF-1 (ng/mL) | 100.1 ± 54.3 | 1133 ± 57.3 | 0.13 |
| Age- and sex-adjusted | 100.9 ± 5.7 | 1123 ± 5.9 | 0.17 |
| Carotid IMT (mm) | 0.72 ± 0.19 | 0.66 ± 0.16 | 0.01 |
25(OH)D, 25-hydroxyvitamin D; BMI, body mass index; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; LDL, low-density lipoprotein cholesterol; hsCRP, high sensitivity C-reactive protein; PTH, parathyroid hormone; IGF-1, insulin-like growth factor-1; IMT, intima-media thickness.