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. Author manuscript; available in PMC: 2015 Nov 12.
Published in final edited form as: Clin Immunol. 2010 Dec 3;138(2):201–211. doi: 10.1016/j.clim.2010.11.002

Figure 1.

Figure 1

Concentration-dependence of effects of thalidomide-type drugs on human T cell generation of cytokines. Each column and bar depicts the mean ± S.D. of the results of cytokine ELISAs of supernates from T cells of a total of four healthy subjects, of whom two were young and two were old, after three days of incubation with anti-CD3 + anti-CD28 antibodies without (control = 100%) and with a drug. The mean ± S.D. of control (100%) values for IFN-γ, IL-2 and IL-17, respectively, were 30,915 ± 11,206, 5.8 ± 3.4 and 1149 ± 372pg/ml.A= IFN-γ, B = IL-2 and C=IL-17. Statistical significance of differences from the controls without an IMD was calculated by a two-sample t test and indicated by + for pb0.05, * for pb 0.01 and ** for pb 0..001.