. Author manuscript; available in PMC: 2015 Nov 12.

Published in final edited form as: Clin Immunol. 2010 Dec 3;138(2):201–211. doi: 10.1016/j.clim.2010.11.002

Table 2.

Effects of lenalidomide on T cell Chemotaxis.

Concentration of lenalidomide (nM)	Response to each chemotactic stimulus (net percentage of initial T cells, mean ± S.D.)
Concentration of lenalidomide (nM)	S1P	CCL5	CCL21
Young subjects
0	2.77±0.70⁺⁺	4.13 ±0.45⁺⁺	37.4±2.7**
10	2.47 ±0.76	3.93 ±0.31	32.3 ± 1.9
100	2.27±0.67	3.60±0.56	35.8±4.3
Old subjects
0	1.70 ±0.36	5.30±0.40	27.8 ±2.9
10	2.10±0.26	5.00±0.87	33.8±2.7⁺
100	2.40±0.10⁺	5.07±0.71	33.2±2.9⁺

Each value is the mean ± S.D. of the results for T cells from three healthy young subjects and three healthy old subjects responding chemotactically to 10 nMS1 P or 100 nM CCL5 or CCL21. The levels of statistical significance of differences in baseline values between T cells of young and old subjects without lenalidomide are depicted by ⁺⁺ = pb0.05 or **=pb0.01. The level of statistical significance of differences between baseline values and those with lenalidomide for T cells of old subjects is depicted by ⁺=pb0.05.