Table 3.
Relapsed, lapsed, smoked in the past 7 days, and validated abstinence at 2- and 6-month follow-ups.
| Quitting outcomes | Group, n (%) | Unadjusted OR (95% CI) | Adjusted ORa (95% CI) | ||||||
|
|
Group A (n=42) |
Group B (n=40) |
Group C (n=54) |
A vs C | B vs C | A vs C | B vs C | ||
| 2-month follow-up |
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Relapse b |
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ITT | 7 (17) | 12 (30) | 23 (43) | 0.27 (0.10, 0.71)e | 0.58 (0.24, 1.37) | 0.26 (0.09, 0.74)f | 0.47 (0.18, 1.25) |
|
|
|
LOCF | 3 (7) | 10 (25) | 13 (24) | 0.27 (0.07, 1.03) | 1.17 (0.45, 3.05) | 0.22 (0.05, 0.95)f | 1.06 (0.35, 3.20) |
|
|
|
Complete case | 2/37 (5) | 10/38 (26) | 13/43 (30) | 0.15 (0.03, 0.71)f | 0.92 (0.35, 2.47) | 0.17 (0.04, 0.77)f | 0.76 (0.24, 2.39) |
|
|
Lapsec | 16 (38) | 15 (38) | 27 (50) | 0.62 (0.27, 1.40) | 0.60 (0.26, 1.38) | 0.65 (0.27, 1.57) | 0.58 (0.23, 1.46) | |
|
|
Smoked in the past 7 days | 7 (17) | 12 (30) | 24 (44) | 0.25 (0.09, 0.66)e | 0.54 (0.23, 1.27) | 0.26 (0.09, 0.73)f | 0.44 (0.17, 1.17) | |
|
|
Validated abstinenced | 16 (38) | 15 (38) | 13 (24) | 1.94 (0.80, 4.69) | 1.89 (0.77, 4.63) | 1.66 (0.64, 4.33) | 1.64 (0.61, 4.39) | |
| 6-month follow-up |
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Relapse b |
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ITT | 17 (41) | 21 (53) | 33 (61) | 0.43 (0.19, 0.99)f | 0.70 (0.31, 1.61) | 0.35 (0.14, 0.86)f | 0.73 (0.29, 1.83) |
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LOCF | 11 (26) | 13 (33) | 20 (37) | 0.60 (0.25, 1.46) | 0.82 (0.35, 1.94) | 0.54 (0.21, 1.40) | 0.75 (0.29, 1.96) |
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Complete case | 9/34 (27) | 9/28 (32) | 17/38 (45) | 0.49 (0.19, 1.31) | 0.59 (0.21, 1.62) | 0.43 (0.15, 1.26) | 0.57 (0.18, 1.79) |
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|
Lapsec | 24 (57) | 22 (55) | 33 (61) | 0.85 (0.37, 1.93) | 0.78 (0.34, 1.78) | 0.71 (0.29, 1.74) | 0.81 (0.32, 2.03) | |
|
|
Smoked in the past 7 days | 15 (36) | 21 (53) | 33 (61) | 0.35 (0.15, 0.82)f | 0.70 (0.31, 1.61) | 0.29 (0.11, 0.72)e | 0.68 (0.27, 1.71) | |
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Validated abstinenced | 11 (26) | 10 (25) | 8 (15) | 2.04 (0.74, 5.65) | 1.92 (0.68, 5.41) | 1.87 (0.62, 5.63) | 2.01 (0.64, 6.36) | |
a Odds ratio adjusted for age, frequency of smoking urge in past month, intensity of smoking urge in past 24 hours, and days of abstinence at baseline.
b Relapse was defined as smoking 5 or more cigarettes in 3 consecutive days in the past 2 and 4 months at 2- and 6-month follow-ups, respectively. Intention-to-treat (ITT) analysis assumed participants who were lost to follow-up as relapsers or smokers. Last observation carried forward (LOCF) assumed participants who were lost to follow-up as the status of previous follow-up. Complete-case analysis excluded participants who were lost to follow-up.
c Lapse was defined as any incidence of smoking in the past 2 and 4 months at 2- and 6-month follow-ups, respectively.
d Validated abstinence (by ITT) was defined as self-reported abstinence validated by tests of exhaled carbon monoxide (≤4 ppm) and salivary cotinine (≤10 ng/mL).
e P<.01.
f P<.05.