Table 1.

Changes in the Oxidative Stress Markers Before and After lGSH Supplementation

Redox changes in the immune cells	Function	Changes in the levels of oxidative stress markers in individuals with HIV infection compared to healthy subjects	Changes in the levels of oxidative stress markers in individuals with HIV infection at 3 months post-supplementation with lGSH
IL-6	Induces oxidative stress and inflammation	16× increase	2× decrease
Oxidative stress	Inflammation and cell death	5× increase in monocytes	6× decrease in monocytes
		2× increase in CD4 T cells	4× decrease in CD4 T cells
		7× increase in CD8 T cells	8× decrease in CD8 T cells
GSH	Antioxidant; has antimycobacterial and immune enhancing effects	12× decrease in PBMC	2× increase in PBMC

GSH, glutathione; IL-6, interleukin-6; lGSH, liposomal GSH; PBMC, peripheral blood mononuclear cell.