Table 1.
Redox changes in the immune cells | Function | Changes in the levels of oxidative stress markers in individuals with HIV infection compared to healthy subjects | Changes in the levels of oxidative stress markers in individuals with HIV infection at 3 months post-supplementation with lGSH |
---|---|---|---|
IL-6 | Induces oxidative stress and inflammation | 16× increase | 2× decrease |
Oxidative stress | Inflammation and cell death | 5× increase in monocytes | 6× decrease in monocytes |
2× increase in CD4 T cells | 4× decrease in CD4 T cells | ||
7× increase in CD8 T cells | 8× decrease in CD8 T cells | ||
GSH | Antioxidant; has antimycobacterial and immune enhancing effects | 12× decrease in PBMC | 2× increase in PBMC |
GSH, glutathione; IL-6, interleukin-6; lGSH, liposomal GSH; PBMC, peripheral blood mononuclear cell.