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. Author manuscript; available in PMC: 2016 Oct 15.
Published in final edited form as: Bioorg Med Chem Lett. 2015 Jul 29;25(20):4683–4688. doi: 10.1016/j.bmcl.2015.07.064

Figure 2.

Figure 2

Ligand 17 was evaluated in SD rats using a radiant heat assay; Ligand 17 dose-dependency was assessed by constructing a dose response curve (top); Ligand 17 antinociceptive dose-response curve (bottom).