Table 3. Melanoma Patients' characteristics (TNM classification) and average concentrations of cfDNA and ctDNA in plasma of melanoma patients.

Patient	Stage	TNM class 1	Therapy	Plasma cfDNA (ng per mL)	BRAF V600E (copies)
1	IV	T3bN0M1c	Ipilimumab	287.5	9.48 per 4 ml
2	IV	T4N3M1c	Vemurafenib	193.2	847.78 per 5 ml
3	III A	T2aN1aM0	Interferon	96	0
4	III C	T4bN2cM0	Interferon	176.1	0
5	II C	T4bN0M0	Interferon	110.4	0
6	IV	T1aN0M1c	Vemurafenib	81.2	32.51 per 4 ml
7	I B	T2aN0M0	Interferon	185.5	0.45 per 5 ml
8	IV	T4bN3M1c	Vemurafenib	176	0.48 per 4 ml
9	IV	T3bN1aM1c	Vemurafenib	209.6	20.06 per 4 ml

¹ According to AJCC classification